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ARACHIDONATE 15-LIPOXYGENASE
Descriptors Found:
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DeCS
Descriptor
English
:
Arachidonate 15-Lipoxygenase
Descriptor
Spanish
:
Araquidonato 15-Lipooxigenasa
Descriptor
Portuguese
:
Araquidonato 15-Lipoxigenase
Synonyms
English
:
15-Lipoxygenase
Tree Number:
D08.811.682.690.416.583.500.065
D12.776.556.579.374.568.500.030
Definition
English
:
An enzyme that catalyzes the
oxidation
of
arachidonic acid
to yield 15-hydroperoxyarachidonate (15-HPETE) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-HETE). The 15-hydroperoxides are preferentially formed in
NEUTROPHILS
and
LYMPHOCYTES.
Entry Combination - descr/qualif
English
:
Arachidonate 15-Lipoxygenase
/
antagonists & inhibitors
use
Lipoxygenase Inhibitors
History Note
English
:
91(87); was see under ARACHIDONATE LIPOXYGENASES 1987-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
19076
Unique Identifier:
D001093
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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